Mast Cells in Bronchiolitis
نویسنده
چکیده
Idiopathic bronchiolitis obliterans organizing pneumonia (BOOP) is characterized by air space in¬ flammation and fibrosis of unknown origin. The pathogenesis of the inflammatory reaction and fi¬ brosis in fibrotic lung disorders remains unclear; however, recent attention has focused on the po¬ tential role ofthe mast cell in the genesis of fibrosis. To determine whether mast cells are implicated in the pathogenesis ofBOOP, mast cells were identified in BAL fluid and in transbronchial lung bi¬ opsy specimens from 11 patients affected by BOOP and 17 control subjects. Mast cells and tryptase
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تاریخ انتشار 2007